Jackson, Doba

Dr. Doba Jackson, a native of Detroit, Michigan, and arrived at Huntingdon College in the fall of 2007. His specializations are biochemistry and structural biology. Dr. Jackson’s research focuses on understanding the chemical and physical principles of that determine the structure of proteins in solutions. The research crosses over several disciplines such as biology, chemistry, physics, and mathematics.

Dr. Jackson’s research accomplishments include: (1) deciphering the interaction between human Rad52 and RPA that is responsible for double-stranded break repair of DNA and breast cancer, and (2) the engineering of novel macromolecule crystal forms of mating-type DNA/proteins complexes such as MATalpha1/MCM1/DNA. In 2003, Dr. Jackson was awarded an NSF-sponsored postdoctoral fellowship for crystallization of mating-type macromolecular complexes. Dr. Jackson research interest also include the structural biology of salmonella bacteriophages and the structure of High Mobility Group (HMG) DNA binding domains.

Dr. Jackson’s main teaching specialty is Biochemistry; however he also teaches Physical Chemistry, Organic Chemistry, General Chemistry, and Critical Thinking in Chemistry. Dr. Jackson is also the pre-medical school advisor and is part of Huntingdon College’s Pre-Health Professions Advisory Committee (HPPC).  Dr. Jackson has won several teaching awards which include: the Exemplary Teaching Award (2023, 2016), Educator of the year (2023), and the Outstanding Teaching Assistant Award (1997).

Publications

1) Holston J., Jackson D., Tao M., High P, Dudley E., Lee H., Demographic and Comorbidity Associations in Chronic Spontaneous Urticaria: A Retrospective Analysis,  Advances in infectious diseases, 2025, 15(2), p262-267

2) Williams J, Venkatsen K, Ayariga JA, Jackson D, Wu H, Villafane R., “A genetic analysis of an important hydrophobic interaction at the P22 TSP N-terminal domain,” (2018) Archives in Virology, Vol 163, issue 6, pp 1623-33

3) Ayariga JA, Venkatesan K, Ward R, Wu H, Jackson D, and Robert Villafane, “Initiation of the p22 infection at the phage centennial,” Frontiers in Science, Technology, Engineering, and Mathematics, published on the web Feb 1st 2018

4) Berch. J., Murphy M., Jackson D., “Using High Risk/Transformative Research Project to Introduce Undergraduate to the Research Process,” (2017) Frontiers in Science, vol. 1, p1-2

5) Murphy M., Jackson D., Carr J., Departmental matriculation ceremonies for first-year majors,” (2017) E-Source for College Transactions, vol. 14, No 2, p8-10

6) Palmer C., Johnston S., Hongzhuan W., Dean D., Jackson D., Villafane R.,“Stem Mutants in the N-terminal domain of the Phage P22 Tailspike protein,” (2014) American Journal of Microbiological Research, Vol. 2, No. 1, p1-7

7) Carr J., Jackson D., Murphy M.K., “Assessment of Educationally Purposeful Activities for First-Generation College Students in a Chemistry Program,” (2014) Esource for College Transactions, 12(1), p4-7

8) Jackson D., Lawson T., Villafane R., Gary L., “Modeling the Structure of Yeast MATα1: An HMG-Box Motif with a C-Terminal Helical Extension,” (2013) Open Journal of Biophysics, Vol. 3 No. 1, pp. 1-12.

9) Jackson D., Dhar K., Wahl J., Wold M.S., Borgstahl G.E.O., Analysis of the human replication protein A/Rad52 complex: evidence for crosstalk between RPA32, RPA70, Rad52 and DNA, (2002), Journal of Molecular Biology, 321, p133-148

10) Ranatunga W., Jackson D., Lloyd J., Forget A., Knight K., Borgstahl G.E.O., Human Rad52 exhibits two modes of self-association, (2001), Journal of Biological Chemistry, 276 (19), p15876-15880

11) Ranatunga W., Jackson D., Flowers R., Borgstahl G.E.O., Human Rad52 has extreme thermal stability, (2001), Biochemistry, 40, p8557-8562 12) Jackson D., (2002) “Analysis of the human Rad52/RPA complex: Characterization of interacting regions, DNA binding activity, and higher-order complexes,” The University of Toledo, PHD Thesis